Health Condition 1: D179- Benign lipomatous neoplasm, unspecified Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patient of either sex between 18 years to 60 years for surgery under general anesthesia belonging to American society of Anaesthesiologist(ASA) Class 1 or 2 with BMI less than 30 and scheduled for elective surgery under general anesthesia will be included in study for comparative evaluation of dexmedetomidine and butorphanol for attenuation of etomidate-induced myoclonus.
Exclusion criteria
Exclusion criteria: 1. Patients with bradycardia (heart rate less than 60 per minute , having arrythmias or AV block, on beta blockers or having pacemaker in situ 2. Known case of hypoadrenalism 3. Pregnant or lactating patients 4. Known hypersensitivity to etomidate 5. Patient refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be measured as the incidence of etomidate-induced myoclonusTimepoint: The participants will be observed for 1 minute after induction of anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome will be measured as observed side-effectsTimepoint: 1 minute interval for initial 10 minutes and then every 5 minutes for 60 minutes;The secondary outcome will be measured as the severity of etomidate-induced myoclonus using 4 point grading scaleTimepoint: 1 minute after induction of anesthesia | — |
Countries
India
Contacts
Dayanand Medical College and Hospital