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To know and compare the action of intravenous and nebulized dexmedetomidine in decreasing hemodynamic response to laryngoscopy and intubation

A study on comparison of intravenous and nebulized dexmedetomidine for attenuation of hemodynamic response to laryngoscopy and intubation - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/08/072305
Enrollment
64
Registered
2024-08-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Intravenous dexmedetomidine: To analyze the files of patients who got intravenous dexmedetomidine(dose 0.5mcg/kg) during surgeries and then to find out effect of it in attenu

Sponsors

Reshma S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 1-2 patients 2.Between the age of 18-60 years 3.Elective surgeries requiring endotracheal intubation for general anaesthesia.

Exclusion criteria

Exclusion criteria: 1.History of dexmedetomidine allergy 2.Patients with anticipated difficult airway 3.Patients with unanticipated difficult intubation 4.Laryngoscopic attempt lasting greater than 15 s or more than one attempt

Design outcomes

Primary

MeasureTime frame
To assess the effect of intravenous dexmedetomidine in attenuating hemodynamic response to laryngoscopy and intubation. To assess the effect of nebulized dexmedetomidine in attenuating hemodynamic response to laryngoscopy and intubation. Timepoint: At the time of intubation then at 1min,3min,5min,10min interval after intubation—

Secondary

MeasureTime frame
To compare preoperative sedation Induction propofol requirements Any adverse effects Timepoint: At time of completion of drug administration at the time of induction up to 10 minutes after intubation—

Countries

India

Contacts

Public ContactDr Reshma S

Amala institute of medical sciences

drpclini@gmail.com9846332776

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026