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Assessment of the effects of smaller drops versus regular sized drops of topical anaesthetic drops

Evaluation of Nanodropper-mediated Microdrops vs Conventional Drops of Proparacaine HCL 0.5 Percentage - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072298
Enrollment
720
Registered
2024-08-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H539- Unspecified visual disturbance

Interventions

Intervention1: Nanodropper-mediated microdrops of proparacaine HCL 0.5%: Each study participant will receive on single drop of proparacaine hydrochloride0.5% following which Conjunctival pinch tests

Sponsors

Nanodropper, Inc.
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients >= 18 years 2) Ability to provide informed consent for mode of topical anesthesia delivery 3) Ability to verbally respond to pain 4) Receiving treatment at AEH OPD (patient has undergone a preliminary examination and is awaiting dilation)

Exclusion criteria

Exclusion criteria: 1)Have a contraindication to local anaesthetics. 2)Intravitreal injection within the past 14 days. 3)Recent ocular surgery within the past 4 weeks. 4)Preexisting diagnosis of ocular surface disease. requiring punctal plug placement. 5)Evidence of any current ocular inflammation/infection. 6)Any previous ocular condition (i.e., neurotrophic keratitis, herpetic eye disease, presence of a corneal graft, etc.) that has permanently altered the native sensation of the ocular surface. 7) Use of contact lenses. 8) Use of exclusionary medications: 9) Topical steroid drops, NSAIDS, IOP lowering eye drops, any anti-viral medications used for herpes, Opioids

Design outcomes

Primary

MeasureTime frame
The results of this study might implicate the nanodropper as a viable and desirable solution to oversized drop-induced waste.Timepoint: 6 months

Secondary

MeasureTime frame
It may further support the revision of existing institutional policies to allow for extended use of multi-dose bottles Timepoint: 6 months

Countries

India

Contacts

Public ContactDr Indira Durai

Aravind Eye Hospital and Postgraduate Institute of Ophthalmology

indiradurai@aravind.org914524356100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026