Health Condition 1: C719- Malignant neoplasm of brain, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Study population will be divided into 3 groups: Group A: Patients with histopathologically proven Low-Grade Glioma or Non- Glial tumor. Group B: Patients with histopathologically proven High-Grade Glioma Group C (Control Population): Age and Gender matched healthy volunteers from Patient’s attendants, hospital staff will be selected as control population.
Exclusion criteria
Exclusion criteria: Pregnant and lactating females. Patients with any systemic illnesses like any malignancy other than leptomeningeal tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Expression of TRIM33 gene in high grade glioma Vs non-glial tumors & low-grade glioma. 2) Methylation status of TRIM33 gene in high grade glioma Vs non-glial tumors & low-grade glioma.Timepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Comparison of expression and methylation status of TRIM33 gene between high grade glioma Vs non-glial tumors & low-grade glioma. 2) Association of expression and methylation status of TRIM33 gene between high grade glioma VS non-glial tumors & low-grade glioma.Timepoint: 1 YEAR | — |
Countries
India
Contacts
G B Pant Institute of Post Graduate Medical Education and Research