Health Condition 1: G00-G99- Diseases of the nervous system Health Condition 2: C719- Malignant neoplasm of brain, unspecified
Conditions
Interventions
Intervention1: Intravoxel incoherent motion - diffusion kurtosis imaging: Dynamic contrast-enhanced perfusion MRI
Intervention2: NIL: NIL
Control Intervention1: Nil: Nil
Sponsors
Manipal College of Health Professions
Eligibility
Inclusion criteria
Inclusion criteria: Phase I: Patients referred for contrast-enhanced MRI brain scan Phase II: Patients with brain tumours who have not undergone surgery or treatment for tumours Patient with brain tumours post-surgery or post-chemo/radiotherapy
Exclusion criteria
Exclusion criteria: Phase I & II: Pregnant patient Uncooperative patients Patients contraindicated for MRI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IVIM: D: True diffusion coefficient D star: Pseudo diffusion coefficient f: Perfusion fraction DDC: Distributed diffusion coefficient Alpha: Heterogeneity Index MK: Mean Kurtosis MD: Mean Diffusivity DSC: CBV: Cerebral Blood Volume CBF: Cerebral Blood Flow MTT: Mean Transit Time TTP: Time to Peak DWI: ADC: Apparent Diffusion CoefficientTimepoint: At the time of scan | — |
Secondary
| Measure | Time frame |
|---|---|
| DDC, alpha and D compared against ADC value in classification of tumoursTimepoint: At the time of scan | — |
Countries
India
Contacts
Public ContactDr Saikiran P
Manipal College of Health Professions, MAHE
Outcome results
None listed