Health Condition 1: K85- Acute pancreatitis
Conditions
Interventions
Intervention1: Transdermal Buprenorphine patch: 10 mcg buprenorphine patch will be applied only once in each patient on bare area of chest/back in patients of acute pancreatitis expriencing pain.
The
Sponsors
Dr Satinder Pal Singla
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient with acute pancreatitis according to revised Atlanta classification. 2.Age = 18 years. 3.Pain on VAS =7 on arrival.
Exclusion criteria
Exclusion criteria: 1.Altered sensorium 2.Patient in shock/on mechanical ventilation 3.Contraindications to administration of opioids 4.Patients on chronic pain medications (taken opioids for more than or equal to 3 months with last intake in last 7 days) • Pregnant/lactating mothers • Chronic pancreatitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the number of acute pancreatitis patients achieving adequate pain relief with transdermal buprenorphine patch to intravenous tramadol. Pain relief in the form of reduction of visual analogue scale score by more than or equal to 3 points or absolute reduction to less than 3 points at 36 hours from enrollment in the trial.Timepoint: 36 hours from enrollment in the trial | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the frequency of rescue analgesia required for adequate pain relief in patients of acute pancreatitis being treated with transdermal buprenorphine patch to intravenous tramadol. 2. To monitor the adverse effects due to opioids treatment in patients of acute pancreatitis being treated for pain. Timepoint: At 24 hours, 36 hours, 48 hours, 72 hours | — |
Countries
India
Contacts
Public ContactSatinder Pal Singla
Kalinga Institute of Medical Sciences
Outcome results
None listed