Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ASA 1-2 Elective upper gastrointestinal surgery
Exclusion criteria
Exclusion criteria: Emergency indication, coagulation disorder, infection at the injection site, recent use of glucocorticoids, known allergy to LA, ASA grade 3 or 4, history of abdominal surgery, or trauma, use of any analgesics in the preoperative 24 h, chronic opioid consumption, alcohol or drugs use, refusal to participate, pregnancy, body mass index (BMI) = 35 kg/m2 known history of alcohol or drug dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total amount of cumulative intraop fentanyl used for analgesiaTimepoint: intraop 4 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. perioperative hemodynamics (SBP,MAP, DBP, HR), 2. complications of BRILMA, M-TAPA block like pneumothorax, intravascular injection, or LA toxicity, 3.the opioids related adverse effects (like nausea & vomiting, sedation, pruritus, constipation, urinary retention, & respiratory depression) 4..time to request for first analgesia, antiemetic consumption, sedation, postoperative nausea and vomiting (PONV), sedation (ramsey sedation score)Timepoint: baseline, induction, intubation, block, post block 5, 10 15 min, peritoneum retraction, post retraction every 15 min till closure at extubation,postop, 2nd hr & 4th hr | — |
Countries
India
Contacts
Nizams Institute of Medical Sciences Hyyderabad: Pincode: 500082