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Comparison of 2 nerve blocks with epidural anaesthesia to reduce pain in abdominal surgery

Comparison between single shot preemptive epidural analgesia MBRILMA and MTAPA blocks on opioid reducing effect in open upper abdominal surgeries A randomised prospective blind study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072143
Enrollment
60
Registered
2024-08-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Epidural anaesthesia group: Will receive single shot epidural anaesthesia with 10 ml of 0.2% plain ropivacaine with 4 mg dexamethasone adjuvant Intervention2: M-TAPA group: Will receiv

Sponsors

Singam Geetha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1-2 Elective upper gastrointestinal surgery

Exclusion criteria

Exclusion criteria: Emergency indication, coagulation disorder, infection at the injection site, recent use of glucocorticoids, known allergy to LA, ASA grade 3 or 4, history of abdominal surgery, or trauma, use of any analgesics in the preoperative 24 h, chronic opioid consumption, alcohol or drugs use, refusal to participate, pregnancy, body mass index (BMI) = 35 kg/m2 known history of alcohol or drug dependence.

Design outcomes

Primary

MeasureTime frame
total amount of cumulative intraop fentanyl used for analgesiaTimepoint: intraop 4 hours

Secondary

MeasureTime frame
1. perioperative hemodynamics (SBP,MAP, DBP, HR), 2. complications of BRILMA, M-TAPA block like pneumothorax, intravascular injection, or LA toxicity, 3.the opioids related adverse effects (like nausea & vomiting, sedation, pruritus, constipation, urinary retention, & respiratory depression) 4..time to request for first analgesia, antiemetic consumption, sedation, postoperative nausea and vomiting (PONV), sedation (ramsey sedation score)Timepoint: baseline, induction, intubation, block, post block 5, 10 15 min, peritoneum retraction, post retraction every 15 min till closure at extubation,postop, 2nd hr & 4th hr

Countries

India

Contacts

Public ContactSingam Geetha

Nizams Institute of Medical Sciences Hyyderabad: Pincode: 500082

singamgeetha11@gmail.com09441043075

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026