Health Condition 1: L700- Acne vulgaris
Conditions
Interventions
Intervention1: Minocycline: 4% gel applied topically over lesions of acne vulgaris once daily for the period of 12 weeks
Control Intervention1: Benzoyl Peroxide: 5% gel applied topically over lesions
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18-35 years of either gender. Females of reproductive age group will be included only if they are not planning to conceive till the end of the study. 2. Patients diagnosed with grade 1 and 2 Acne vulgaris according to acne grading criteria of Indian Association of Dermatologists, Venereologists and Leprologists (IADVL). 3. Patients willing to give written informed consent.
Exclusion criteria
Exclusion criteria: 1. H/o hypersensitivity to any drugs. 2. Patients having any history of medical condition considered significant by the investigator. 3. Use of systemic antibiotics and steroids in the last month prior to the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To compare the mean change in the Investigators Global Assessment (IGA) score for Acne from the baseline to 12 weeks in two treatment armsTimepoint: baseline,4 weeks, 8 weeks, 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Change in quality of life using Cardiff Acne Disability Index (CADI). from baseline to 12 weeks in two treatment arms. 2.Incidence of adverse effects in two treatment arms. Timepoint: Baseline,4 weeks, 8 weeks, 12 weeks | — |
Countries
India
Contacts
Public ContactDr M Padmaja
Nizams Institute of Medical Sciences
Outcome results
None listed