Comparison between two drugs for preventing shivering after giving spinal anaesthesia in lower abdominal surgeries

Comparison of prophylactic administration of Ondansetron and Dexmedetomidine for the prevention of post-spinal anaesthesia shivering in lower abdominal surgeries : A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072116

Enrollment

Registered

2024-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: Inj. Ondansetron: Study participants will be randomized into three groups. Group B will receive 0.1 mg/kg Ondansetron diluted to a volume of 5 ml, by intravenous route over five minutes

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of age group 18 to 60 years. 2. Patients of American Society of Anaesthesiologists (ASA) grade I or II.

Exclusion criteria

Exclusion criteria: 1. Patients with history of allergy to Ondansetron and Dexmedetomidine. 2. Patients with history of diabetes, hypertension, thyroid disorder, cardiovascular, respiratory, renal, hepatic or neurological disease. 3. Patients with pregnancy. 4. Patients with body temperature less than 36.5 degree Celsius or more than 38 degree Celsius. 5. Patients with local site infection. 6. Patients with spinal deformity. 7. Patients with bleeding disorder- platelet count less than 50,000/microlitre, prothrombin time more than 14 sec, International normalized ratio (INR) more than 1.5

Design outcomes

Primary

Measure	Time frame
Post spinal anaesthesia shiveringTimepoint: Outcome will be assessed during the intraoperative period.	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactGojendra Rajkumar

Regional Institute of Medical Sciences, Imphal, Manipur

gojendrar68@gmail.com9862824562

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026