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A Clinical study to explore the correlation between WBCs and Cholesterol Ratio as Biomarker in Chronic Periodontitis patients

Assessment of Monocyte-to-High Density Cholesterol Ratio and the Delta Neutrophil Index as potential biomarkers in Chronic Periodontitis: A Cross-sectional study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072085
Enrollment
60
Registered
2024-08-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Moderate Periodontitis: At least more than two teeth with periodontal pocket depth of more than 3mm and clinical attachment loss of 4mm Intervention2: Severe Periodontitis: At least mo

Sponsors

Dr Aarti Patil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Within the age group of 25 to 58 years. 2. Patients having at least 20 teeth (not including third molars and teeth with orthodontic appliances, bridges, crowns, or implants). 3. Gingival Index scoring of 0 for clinically Healthy Gingiva. 4. At least =2 teeth with one or more sites with probing pocket depth (PD) =3 mm and clinical attachment loss (CAL) of 3-4mm for moderate periodontitis and 5mm or more for severe periodontitis. 5. Patients who are willing to participate in the study and given their written consent.

Exclusion criteria

Exclusion criteria: 1. Patients having Systemic illnesses (i.e., diabetes mellitus, cancer, human immunodeficiency syndrome, hepatic diseases, bone metabolic diseases, cardiovascular diseases, lung diseases, malignancies or disorders that compromise wound healing, radiation, or immunosuppressive therapy) 2. Smokers and chronic alcoholic patients. 3. Pregnant or lactating women. 4. Chronic use of NSAIDs and periodontal therapy within the previous 3 months. 5. Patients on lipid lowering drugs. 6. Patients who are not willing to participate

Design outcomes

Primary

MeasureTime frame
To assess the Monocyte-to-High Density Cholesterol Ratio and the Delta Neutrophil Index as a potential Biomarker in Chronic Periodontitis Patients.Timepoint: Baseline

Secondary

MeasureTime frame
To evaluate the effect of Chronic Periodontitis on the levels of cholesterol in the body.Timepoint: Baseline

Countries

India

Contacts

Public ContactDr Aarti Yashwant Patil

JMFs ACPM Dental College Dhule

dralkawaghmare@gmail.com9423918900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026