Comparision between two solutions for reducing the bacterial count in root canal of primary teeth.

Comparative evaluation of antibacterial efficacy of 2 percent Chlorhexidine and 6 percent Chitosan as irrigating solutions in nonvital primary teeth An invivo study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072051

Enrollment

Registered

2024-08-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Chitosan irrigating solution: Antibacterial efficacy of Chitosan will be evaluated by comparing the pre and post irrigation sample taken from root canal of non-vital primary teeth. Cont

Eligibility

Inclusion criteria

Inclusion criteria: Primary teeth with chronic pulpitis, chronic periapical abscess, acute exacerbation of chronic pulpitis, and chronic periapical abscess Primary molars with minimal mobility and restorable crown Minimal root resorption No sinus tract Parents/caregivers acceptance and cooperation.

Exclusion criteria

Exclusion criteria: Teeth having furcal lesions more than 5 mm diameter or periapical lesions exceeding 10 mm diameter. Children with systemic diseases and patients undergone antibiotic therapy in the past 3 months. Children whose parents have refused to participate in the study.

Design outcomes

Primary

Measure	Time frame
Evaluation of bacterial load before and after irrigation to assess the antibacterial efficacy of 2% Chlorhexidine and 6% Chitosan in pediatric patientsTimepoint: Baseline (Before Intervention): Pre-treatment microbial sampling will be collected immediately after access opening Post-irrigation (After Intervention): Sample will be collected 30 minutes irrigation to assess the reduction in bacterial load.	—

Measure

Time frame

Evaluation of bacterial load before and after irrigation to assess the antibacterial efficacy of 2% Chlorhexidine and 6% Chitosan in pediatric patientsTimepoint: Baseline (Before Intervention): Pre-treatment microbial sampling will be collected immediately after access opening Post-irrigation (After Intervention): Sample will be collected 30 minutes irrigation to assess the reduction in bacterial load.

—

Secondary

Measure	Time frame
Antibacterial efficacy of two different irrigants usedTimepoint: Pre-irrigation and post-irrigation	—

Countries

India

Contacts

Public ContactDr Shere Shraddha Vivekanand

NIMS University

chaya.chhabra@gmail.com7745073955

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026