comparative evaluation of three different root canal medicaments in reducing pain

Comparative evaluation of the efficacy of Calcium Hydroxide, Triple Antibiotic Paste and Calcium Hydroxide with 2% Chlorhexidine as intracanal medicament in reducing interappointment pain during endodontic treatment: an in vivo study - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/071970

Enrollment

Registered

2024-08-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Calcium Hydroxide paste: RC Cal (PRIME) will be inserted in the root canals and left there for 72 hours followed by irrigation Control Intervention1: Triple Antibiotic Paste: Ciprofloxa

Eligibility

Inclusion criteria

Inclusion criteria: 1 Teeth with symptomatic irreversible pulpitis 2 Teeth with acute and chronic apical periodontitis 3 Teeth with pulpal necrosis 4 Patients in the age group of 20 and 45 years.

Exclusion criteria

Exclusion criteria: 1 Patients with systemic disease. 2 Pregnant and lactating women. 3 Teeth with incomplete root formation 4 Teeth with severe periodontal problem 5 Teeth requiring retreatment 6 Inability to provide informed consent. 7 Patients having more than one tooth requiring root canal treatment

Design outcomes

Primary

Measure	Time frame
To compare the effectiveness of Calcium Hydroxide, Triple Antibiotic Paste and Calcium Hydroxide with 2% Chlorhexidine as intracanal medicament in reducing interappointment pain during endodontic treatmentTimepoint: 18 months	—

Secondary

Measure	Time frame
To know which intracanal medicament is more effective in reducing interappointment pain during endodontic treatmentTimepoint: 18 months	—

Countries

India

Contacts

Public ContactDr Itika Jain

NIMS Dental College and Hospital

shyam.agarwal@nimsuniversity.org9829506983

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026