Evaluating changes in orthodontic tooth movement with use of different blood derivatives.

A comparative evaluation of efficacy of leukocyte- platelet-rich fibrin (L-PRF) and injectable-platelet rich fibrin (I-PRF) on the rate of canine retraction: A split mouth, randomized controlled trial - PRF

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/071908

Enrollment

Registered

2024-08-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Individual canine retraction with application of Leukocyte-platelet rich fibrin (Group 1) and Injectable - platelet rich fibrin : submucosal ( group 2) and Injectable- platelet rich fib

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with age ranging from 13 to 25 years 2.Class 1 or Class 2 malocclusion requiring maxillary first premolar extractions. 3.No canine root prominence 4.Patient with no radiographic evidence of bone loss 5.Patient with no systemic disease

Exclusion criteria

Exclusion criteria: 1.history of previous orthodontic treatment 2.medication intake such as nonsteroidal anti-inflammatory drugs 3.metabolic disorder or syndrome affecting calcium and phosphate metabolism 4.blood disorders like thrombocytopenia and leukopenia,

Design outcomes

Primary

Measure	Time frame
To compare and evaluate the rate of orthodontic tooth movement by L PRF insertion in extraction sockets, I PRF injected submucosally, I PRF injected intra ligamentally. Timepoint: 4 months	—

Secondary

Measure	Time frame
To compare and evaluate the effects of L-PRF and I-PRF on root resorption.Timepoint: 4 months	—

Countries

India

Contacts

Public ContactDr Aastha Kamrani

Subharti Dental College

dramitkkhera@gmail.com8057143083

Outcome results