To compare the effect of two drugs Dexmedetomidine and Dexamethasone on decreasing the postoperative sore throat.

Efficacy of Dexmedetomidine and Dexamethasone gargle on postoperative sore throat: A randomized double blind clinical study. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/071899

Enrollment

120

Registered

2024-08-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: 25 ml solution of gargle of dexmedetomidine(.5 microgram/kg) diluted with .9% normal saline will be given to group(A) patients by oral rout 5 minute before the inducti

Eligibility

Inclusion criteria

Inclusion criteria: Patients age: 20 to 45 years. Patients of ASA Physical Status classification I and II. Patients requiring endotracheal intubation in laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: Preoperative sore throat. Patients with history of recent upper respiratory tract infection. Chronic smokers. History of allergy to study drugs. Intubation unsuccessful in first attempt. Pregnant patients.

Design outcomes

Primary

Measure	Time frame
The sore throat and cough will be assessed by interviewing the patients.Timepoint: Immediately after extubation. After 2 hour in post anaersthesia care unit. After 6 hour in post anaesthesia care unit. After 12 hour in post anaesthesia care unit. After 24 hour in post anaesthesia care unit.	—

Secondary

Measure	Time frame
To compare the severity of cough in grougs. To compare the perioperative hemodynamic parameters To compare the complication ,if anyTimepoint: Before the intubation Immediately after the extubation At 15 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes.;To compare the severity of cough in grougs. To compare the perioperative hemodynamic parameters To compare the complication ,if anyTimepoint: Before the intubation Immediately after the extubation At 15 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes.;To compare the severity of cough in grougs. To compare the perioperative hemodynamic parameters To compare the complication ,if anyTimepoint: Before the intubation Immediately after the extubation At 15 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes.	—

Measure

Time frame

To compare the severity of cough in grougs. To compare the perioperative hemodynamic parameters To compare the complication ,if anyTimepoint: Before the intubation Immediately after the extubation At 15 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes.;To compare the severity of cough in grougs. To compare the perioperative hemodynamic parameters To compare the complication ,if anyTimepoint: Before the intubation Immediately after the extubation At 15 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes.;To compare the severity of cough in grougs. To compare the perioperative hemodynamic parameters To compare the complication ,if anyTimepoint: Before the intubation Immediately after the extubation At 15 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes.

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Countries

India

Contacts

Public ContactJay Brijesh Singh Yadav

UTTAR PRADESH UNIVERSITY OF MEDICAL SCIENCES

drjaybrijesh@gmail.com9368177577

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026