A Study to know the effect of Rasaganthi mezhugu (Internal) and Powthira kalimbu (External) for the management of Powthiram (fistula-in-ano)

An open clinical trial to evaluate the effectiveness of Rasaganthi Mezhugu (Internal) and Powthira Kalimbu (External) in the management of Powthiram (fistula-in-ano) among patients attending Ayothidoss Pandithar Hospital,National Institute of Siddha. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/071813

Enrollment

Registered

2024-08-02

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K603- Anal fistula

Interventions

Intervention1: Rasaganthi Mezhugu (Internal) and Powthira Kalimbu (External): Internal medicine is a Compound Herbo mineral drug indicated to treat fistula in ano advised to intake 500mg twice a day f

Eligibility

Inclusion criteria

Inclusion criteria: 1.Pus, blood and watery discharge from perianal and anal region. 2.Fistula tract – =5 cm 3.patient who have low anal fistula. 4.Patient who are willing to undergo kaarathiri therapy. 5.Willing to give specimen of blood for investigation whenever required. 6.Willing to attend OPD or admission in IPD. 7.Willing to take photograph before and after treatment 8.Patient already presenting with MRI fistulogram ( Recent one month ) or willing to get the MRI from recognized laboratory (based on St James University Hospital MRI classification for fistula ).

Exclusion criteria

Exclusion criteria: 1.Tuberculosis (Genito urinary tract). 2.Hepatitis B & C. 3.Hemophilia and bleeding disorders. 4.Pregnancy & Lactation. 5.Uncontrolled diabetes. 6.K/H/O Coronary Heart Diseases and other cardiac ailments. 7.HIV, Syphilis. 8.K/H/O Crohn’s disease. 9.High anal fistula and complicated fistula. Rectal prolapse. 10.K/H/O Rectal carcinoma. 11.K/H/O Ulcerative colitis

Design outcomes

Primary

Measure	Time frame
Primary outcome will be assessed by Peri-anal Disease Activity Index (PDAI) and good outcome of PDAI score becoming zeroTimepoint: 96 days	—

Secondary

Measure	Time frame
To measure the unit cutting time by using unit cutting time formulaTimepoint: 90 days or till the tract heals whichever comes early	—

Countries

India

Contacts

Public ContactDr H Nalini sofia

National Institute of Siddha

drhnalinisofia@gmail.com8939899363

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026