Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified Health Condition 2: J988- Other specified respiratory disorders
Conditions
Interventions
Intervention1: Tablet Doxophylline: Dosage-650 mg Sustained release
Per oral
Once daily
For 3 months
Control Intervention1: Triple drug inhaler therapy
Formeterol fumarate,
Budesonide,
Glycopyronium
Sponsors
SRM medical college hospital
Eligibility
Inclusion criteria
Inclusion criteria: At least 6 months of diagnosis of chronic obstructive pulmonary disease, according to GOLD guidelines.(Baseline post bronchodilator forced expiratory volume is less than 50% of predicted value.)
Exclusion criteria
Exclusion criteria: .Patient with bronchial asthma, tuberculosis, lung tumour, bronchiectasis, pneumonia or other diseases that might affect pulmonary function or ventilation. 2. Patients with acute exacerbation of COPD. 3.Patients with congestive heart failure, unstable arrhythmias, chronic hypotension, active peptic ulcer disease, recent myocardial infarction and severe liver/kidney disease. 4.Patients who are unable to take Dry powder/Metered dose inhaler effectively even after adequate training.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Improvement in symptoms using Chronic obstructive pulmonary disease assessment test scoring scale. 2.Spirometry 3.Six minute walk test Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of exacerbationsTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactBhagiradhi Thimmapuram
SRM MEDICAL COLLEGE HOSPITAL AND RESEARCH INSTITUTE
Outcome results
None listed