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A randomised control study to analyse the effectiveness of antifungal and steroid nasal douching in allergic fungal rhinosinusinitis

A randomised control trial on the effectiveness of antifungal and steroid nasal douching in allergic fungal rhinosinusinitis a clinical, radiological and biochemical corelation - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071702
Enrollment
40
Registered
2024-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration

Interventions

Intervention1: Budesonide douching, Tab Prednisolone, Tab Itraconazole: Tablet prednisolone per orally 1 mg/kg/day for 7 days, 0.8 mg/kg for 7 days, 0.6 mg/kg for 7 days, 0.4 mg/kg for 7 days followe

Sponsors

Aiims New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Willing to participate in the study Above 14 years of age

Exclusion criteria

Exclusion criteria: Patients not tolerating treatment Complicated afrs Uncontrolled chronic systemic illness(anticipating toxicity of steroid and itraconazole)

Design outcomes

Primary

MeasureTime frame
Pre and post treatment clinical(SNOT 22 and Meltzer endoscopic scores) and radiological (Lund Mackay and 20 point score) comparison in afrs.Timepoint: Baseline and at 6 weeks—

Secondary

MeasureTime frame
Pre & post treatment serological (total serum IgE levels specific IgE levels Absolute eosinophil counts serum Interleukin 5 levels serum galactomannan nasal douches galactomannan) comparison in afrs Timepoint: Baseline & at 6 weeks—

Countries

India

Contacts

Public ContactDr Hitesh Verma

Aiims New Delhi

drhitesh10@gmail.com9868397480

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026