Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Carbetocin: After delivery of baby and clamping of umbilical cord, measurement of hemodynamic parameters will be done and denoted as T0. 100 mcg carbetocin 10 ml dilution with NS/ RL o
Sponsors
Department of Anesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy pregnant woman under going elective lower segment cesarean section at term under spinal anesthesia concerning to be part of study. 2. Patients aged between 18 to 35 years of age.
Exclusion criteria
Exclusion criteria: 1. Women with known sensitivity to heat-stable carbetocin or oxytocin 2. Pregnancy with high risk of PPH 3. Pregnancy with other comorbidities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare changes in maternal hemodynamic parameters (heart rate, systolic and diastolic blood pressure, mean arterial pressure, ST index and O2 saturation) with use of oxytocin and carbetocin in elective lower segment caesarean section.Timepoint: After drug administration, hemodynamic parameters will be recorded at 0, 1, 3, T5, T10, T15, and T30 mins. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the incidence of intraoperative & postoperative feeling of warmth, chest pain, shortness of breath, palpitations, flushing, headache, nausea/ vomiting & chest discomfort.Timepoint: Patient will be assessed at 10,20,30, 60 minutes post operatively.;To compare uterine tone & need of additional uterotonics with use of oxytocin & carbetocin.Timepoint: Uterine tone will be assessed after 20 minutes of drug administration. | — |
Countries
India
Contacts
Public ContactDr Mathangi Krishnakumar
St John’s medical college hospital
Outcome results
None listed