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Early detection of Kidney failure by plasma markers in patients undergoing emergency laparotomy surgery.

Evaluation of plasma microRNA-21 for Early Detection of Postoperative Acute Kidney Injury in patients undergoing exploratory laparotomy: A Prospective Observational Study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/07/071699
Enrollment
100
Registered
2024-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Nil: Nil

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) Physical Status (PS) IE & IIE

Exclusion criteria

Exclusion criteria: Pre-existing renal dysfunction. Patient presenting for redo surgery or surgery due to blunt or penetrating trauma. Patients with preoperative altered mental status, hemodynamic instability or respiratory distress.

Design outcomes

Primary

MeasureTime frame
Blood level of preoperative mi-RNA-21-5p and risk of post operative AKI progression.Timepoint: 4 hours after surgery.—

Secondary

MeasureTime frame
Association of miRNA levels and severity of AKITimepoint: 4 hours after surgery.;Blood levels of preoperative miRNA-146-5p and risk of Postoperative AKI progression.Timepoint: 4 hour after surgery—

Countries

India

Contacts

Public ContactDr Sukhyanti Kerai

Maulana Azad Medical College.

drsukhi25@gmail.com9968527122

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026