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In patients of a fungal skin problem called superficial dermatophytosis which is better among Itraconazole and Itraconazole with Isotretnoin?

Safety and efficacy of oral itraconazole versus oral itraconazole with isotretinoin in chronic and recurrent superficial dermatophytosis A randomized trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071678
Enrollment
70
Registered
2024-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere

Interventions

Intervention1: Combination of Tablet Itraconazole 100mg and Tablet Isotretinoin 20mg: Intervention group will have 35 patients and receive tablet Itraconazole 100mg two times a day in combination with

Sponsors

Bhagat Phool Singh Govt. Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients in the age group of 18 to 60 years who are clinically diagnosed with tinea corporis and cruris with more than 20% BSA and duration of infection is more than 6 months with KOH positive preparation attending the dermatology Out Patient Department of BPS GMC(W) Khanpur Kalan, Sonepat.

Exclusion criteria

Exclusion criteria: 1) Patients with tinea capitis and onychomycosis. 2) Patients with tinea for less than 6 months or limited tinea involving less than 20% of body surface area. 3) Any patient who took itraconazole for tinea in last one year. 4) Patients with liver diseases, renal diseases and ischaemic heart diseases. 5) Patients with hyperlipidaemia. 6) Patients currently on immunosuppressive and corticosteroid therapy. 7) Pregnant and lactating women and females of reproductive age who cannot or refused to take contraceptive pills

Design outcomes

Primary

MeasureTime frame
Clinical assessment score, Global assessment indexTimepoint: Baseline, 2 & 4weeks

Secondary

MeasureTime frame
KOH examination, CBC, LFT, lipid profile, urine pregnancy testTimepoint: Baseline, 2 & 4weeks

Countries

India

Contacts

Public ContactDr Usha Chhillar

BPS GMC (W), Khanpur Kalan

nidhiyadav88@gmail.com9953000599

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026