Effect of Ascorbic acid on postendodontic pain.

Effect of Ascorbic acid on occurrence and severity of post endodontic pain following root canal treatment on teeth with irreversible pulpitis. A triple-blind randomized placebo-controlled trial - nil

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071647

Enrollment

Registered

2024-07-31

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: ASCORBIC ACID OR VITAMIN C 500mg: It will be given to the patients orally, one hour preoperatively. Control Intervention1: PLACEBO CONTROL GROUP: A placebo multivitamin tab will be give

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patients having a tooth with symptomatic irreversible pulpitis and normal periapical radiographic appearance.

Exclusion criteria

Exclusion criteria: Presence of systemic disorders, a sensitivity to lidocaine with 1:80,000 epinephrine or a history of gastrointestinal ulcers, lactation, pregnancy, using any type of analgesic medication in the preceding 12 hours before the treatment, having a tooth not suitable for restoration, and having a full crown

Design outcomes

Primary

Measure	Time frame
Success of preoperative ascorbic acid in reducing post-endodontic pain post-operatively after endodontic treatment.Timepoint: 4hrs, 8 hrs, 12 hrs, 24 hrs and 48 hrs postoperatively	—

Secondary

Measure	Time frame
Compare the effects of ascorbic acid & placebo on post-endodontic pain reduction after endodontic treatment.Timepoint: 4 hrs 8 hrs 12 hrs 24 hrs & 48 hrs	—

Countries

India

Contacts

Public ContactDr Shahnaz

Faculty Of Dentistry, Jamia Millia Islamia

shahnaz@jmi.ac.in7006577811

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026