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A Comparison of Two Treatments for Receding Gums: Using Titanium Platelet Rich Fibrin (T-PRF) vs. Connective Tissue Graft (CTG) with a Special Tunnel Technique

Comparative evaluation of effectiveness of titanium platelet rich fibrin (T-PRF) and connective tissue graft (CTG) harvested from tuberosity area using modified vestibular incision supra periosteal tunnel access (M-VISTA) for management of human gingival recession defects – A Randomized Controlled Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071619
Enrollment
24
Registered
2024-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Titanium platelet rich fibrin (T-PRF): Titanium Platelet-Rich Fibrin (T-PRF) is an advanced regenerative material increasingly used in periodontics for enhancing wound healing and tissu

Sponsors

Datta Meghe Institute oh Higher Education and Research Sawangi Wardha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically healthy patients. 2. Non-smoker, greater than 18 years old at the time of surgery. 3. Teeth presenting Miller class I or II areas having multiple GR on the buccal or labial surfaces, present in either the maxilla or mandible. 4. GR depth of = 2 mm. 5. X-ray of adequate interdental bone (separation across crestal bone and CEJ = 2 mm).

Exclusion criteria

Exclusion criteria: 1. Smokers and patients using tobacco products. 2. Uncooperative subjects. 3. Inadequate oral hygiene and a plaque score =1 after nonsurgical treatment. 4. Record of periodontal surgical treatment in the division chosen for the research. 5. Pregnant woman or lactating mother. 6. Mobile teeth and severely decayed teeth. 7. Irregularly placed teeth.

Design outcomes

Primary

MeasureTime frame
The outcome of this study is to assess the effectiveness of connective tissue graft (CTG) harvested from tuberosity area and Titanium platelet rich fibrin (T-PRF) using M-VISTA technique in multiple gingival recession defects. Timepoint: baseline, 4 weeks, 8 weeks

Secondary

MeasureTime frame
The surgical procedure for the control group would be same as test group procedure with deviation that T-PRF clot will be placed using M-VISTA technique on the recession defect area. Timepoint: 3 months, 6 months & 1 year

Countries

India

Contacts

Public ContactDr Sanehi Devidas Punse

Datta Meghe Institute of Medical Science

drprasaddhadse@gmail.com9822689401

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026