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This study compares nebulized magnesium sulfate and nebulized lignocaine to see which better to control heart rate ,blood pressure ,mean arterial pressure and spo2 , when they get a tube put into trachea and ventilated during surgery.

Nebulised magnesium sulphate v/s nebulised 2 percent lignocaine for attenuation of hemodynamic stress response to laryngoscopy and tracheal intubation: A prospective randomised double blinded ,comparative study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071588
Enrollment
128
Registered
2024-07-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium sulphate: Magnesium sulfate is a magnesium salt having sulfate as the counterion. It has a role as an anticonvulsant, a cardiovascular drug, a calcium channel blocker, an anae

Sponsors

Dr Ashwitha P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18 and 60 years, American Society of Anesthesiologists (ASA) physical status I and II Mallampati grading I to II, Patients who are undergoing elective surgery requiring endotracheal intubation

Exclusion criteria

Exclusion criteria: Patient refusal Patient belonging to ASA physical status 3 or 4 Patient with known hypersensitivity to lignocaine or magnesium sulphate Body mass index more than 30kg/m2 history of cardiovascular diseases like ischaemic heart disease and uncontrolled hypertension Mallampati grading 3 or4

Design outcomes

Primary

MeasureTime frame
To compare haemodynamic stress response to laryngoscopy and tracheal intubationTimepoint: 1hr—

Secondary

MeasureTime frame
To observe changes in spo2Timepoint: 1hr—

Countries

India

Contacts

Public ContactDr ASHWITHA P

Kidwai memorial institute of oncology ,Bangalore

drshashi_2007@yahoo.co.in9008028611

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026