Health Condition 1: O- Medical and Surgical Health Condition 2: L511- Stevens-Johnson syndrome
Conditions
Interventions
Intervention1: 20% Umbilical cord blood serum eye drops (in saline): This will be given 4 times a day for three months
Intervention2: Low Dose Heparin Eye drop (100ui/ml): this will be administered fo
Sponsors
Dr R.P.Centre for Ophthalmic Sciences, AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: a) Patients diagnosed with acute SJS with ocular involvement. b) Aged 18 years or older. c) Willing to provide informed consent
Exclusion criteria
Exclusion criteria: a) Patients with a history of pre-existing ocular conditions that could interfere with the study results. b) Patients with known allergies to any of the study components. c) Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in best corrected visual acuity (BCVA)Timepoint: Day 0, Day 3, Day 7, Day 14, Day30, Day 60, Day 90, Day 120, Day 150, Day 180. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Ocular pain and discomfort (OSDI questionnaire) 2. Severity scoring of ocular manifestations (Gregory et al grading system)Timepoint: Day 0, Day 3, Day 7, Day 14, Day30, Day 60, Day 90, Day 120, Day 150, Day 180. | — |
Countries
India
Contacts
Public ContactDr Namrata Sharma
AIIMS, New Delhi
Outcome results
None listed