Effect of single dose of antihistaminics on psychomotor functions in healthy human volunteers: A Clinical Trial

Effect of single dose Bilastine, desloratadine, chlorpheniramine and placebo on psychomotor functions in healthy human volunteers: A double blind placebo controlled cross over design clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071575

Enrollment

Registered

2024-07-30

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Tab Bilastine 20 mg: 20 mg to be given orally as a single dose with glass of water. Control Intervention1: Tab Chlorpheniramine maleate 4 mg: 4 mg to be given orally as a single dose w

Eligibility

Inclusion criteria

Inclusion criteria: 1.The volunteers from the second MBBS students of AIIMS Raipur willing to participate in the study by giving informed written consent. 2.Age above 18 years 3.The volunteers having no abnormality in general and systemic examination as revealed by detail history and clinical examination

Exclusion criteria

Exclusion criteria: 1. Hepatic disease 2. Renal disease 3. Individuals receiving cardiovascular drugs, sedatives, antianxiety drugs and other antihistamines. 4. H/o treatment with ß2 agonists 5. Hyperthyroidism 6. Individuals suffering from any disease like cardiovascular disease, anxiety disorder or any other chronic illness 7. History of allergy, hypersensitivity to any medications. 8. Known case of colour blindness 9. Having impaired hearing 10. Suffering from essential tremors 11. Complaint of night blindness 12. Essential Tremors 13. K/C/O Epilepsy and H/O seizures.

Design outcomes

Primary

Measure	Time frame
To determine the percentage of healthy human volunteers having different effect on psychomotor functions with single dose Bilastine, desloratadine, chlorpheniramine and placebo.Timepoint: at baseline, 2hours and 4 hours	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Yogendra Narayanrao Keche

AIIMS Raipur

drynkeche@aiimsraipur.edu.in8818882119

Outcome results