Comparing the effectiveness of nebulization dexmedetomidine and lignocaine on control of hemodynamic response to laryngoscopy and intubation

Comparison of effectiveness of preoperative nebulization of dexmedetomidine one microgram per kilogram and lignocaine four percent three milligram per kilogram on control of hemodynamic response to laryngoscopy and intubation prospective randomized double blind study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071554

Enrollment

Registered

2024-07-30

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Neb lignocaine: Nebulization of either dexmedetomidine or lignocaine given via jet nebulizer for 10 minutes duration Control Intervention1: Neb dexmedetomidine: Comparing the effectiven

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient age: 18-60 years of either gender. 2. Patients posted for surgery requiring general anaesthesia. 3. Patient with controlled hypertension.

Exclusion criteria

Exclusion criteria: 1. Patient who does not give written inform consent. 2. Patients with history of allergy to study drug. 3. Patients with anticipated difficult intubation. 4. Patient taking amphotericin B, diazepam, dihydroergotamine.

Design outcomes

Primary

Measure	Time frame
To measure and compare the control of hemodynamic response in terms of heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure to laryngoscopy and intubation in group D and group LTimepoint: 1.5 year	—

Secondary

Measure	Time frame
To observe complication and side effect in both groupTimepoint: 1.5 year	—

Countries

India

Contacts

Public ContactDr Lopa Trivedi

Goverment Medical Collage, Bhavnagar

trivedi_lopa@yahoo.in9428009958

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026