To compare the incidence of post operative delirium with dexmedetomidine and fentanyl in postoperative cardiac patients 12th hourly for 7 days in ICU.

Incidence of Delirium with Dexmedetomidine compared with fentanyl based therapy in post operative cardiac surgical patients:A Randomized controlled single blinded study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071553

Enrollment

150

Registered

2024-07-30

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system Health Condition 2: I20-I25- Ischemic heart diseases

Interventions

Intervention1: Dexmedetomidine,Fentanyl: incidence of Delirium with Dexmedetomidine compared with fentanyl based therapy in post operative cardiac surgical patients. Intervention2: Dexmedetomidine: De

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of age group 18-80 years scheduled for on pump cardiac surgeries.

Exclusion criteria

Exclusion criteria: 1.Patients not giving consent 2.Patients with severe congestive heart failure,(ejection fraction less than 40),second degree heart blocks,neurological disorders,renal and liver failures. 3.If patient is hypotensive preoperatively. 4.If patient baseline heart rate is less than 55per min. 5.If patient has pacemaker insitu. 6.Patient getting reoperated. 7.Patient hypersensitive to opioids and known drug allergies.

Design outcomes

Primary

Measure	Time frame
To compare the incidence of postopertive delirium(confusion assessment method)with dexmedetomidine and fentanylTimepoint: 12th hourly for 7 days.	—

Secondary

Measure	Time frame
Duration of sedation and analgesia,trail of extubation done after 12 hours of shifting the patient to ICU, ,incidence of tachyarrythmias,haemodynamic parameters(HR,MAP,SPO2) and side effects like nausea and vomitingsTimepoint: 2,,6,12,24,48 hourly-sedation and analgesia	—

Countries

India

Contacts

Public ContactPavani paidi

Institue of medical science and sum hospital.

drranjitaacharya@gmail.com8763421899

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026