Treatment of localized hair loss over the scalp using newer modalities.

Cryotherapy with intralesional steroids Versus intralesional pentoxifylline in the treatment of Recalcitrant Alopecia Areata: A Randomised Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071528

Enrollment

Registered

2024-07-30

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L638- Other alopecia areata

Interventions

Intervention1: 1.Cryotherapy with intralesional steroids: Cryotherapy with intralesional injection of triamcinolone acetonide 5mg/ml done every 2 weeks for maximum of 5 sittings Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: Patients with clinical features suggestive of Recalcitrant alopecia areata over the scalp.

Exclusion criteria

Exclusion criteria: 1.Patients with other systemic illness- cardiac hepatic and renal disorders 2.cold intolerance 3.pregnant and lactating women 4.patient not willing for study 5.severely immunocompromised individuals

Design outcomes

Primary

Measure	Time frame
1.Assessment of hair growth with Global Photographic Assessment scale. 2.Assessment of side effects of cryotherapy with intralesional steroids and intralesional pentoxifyllineTimepoint: 1.Assessment of hair growth with Global Photographic Assessment scale at 1st 2nd 3rd 4th 5th sittings 2.Assessment of side effects of cryotherapy with intralesional steroids and intralesional pentoxifylline at 1st 2nd 3rd 4th 5th sittings	—

Measure

Time frame

1.Assessment of hair growth with Global Photographic Assessment scale. 2.Assessment of side effects of cryotherapy with intralesional steroids and intralesional pentoxifyllineTimepoint: 1.Assessment of hair growth with Global Photographic Assessment scale at 1st 2nd 3rd 4th 5th sittings 2.Assessment of side effects of cryotherapy with intralesional steroids and intralesional pentoxifylline at 1st 2nd 3rd 4th 5th sittings

—

Secondary

Measure	Time frame
1.Assessment of hair growth with Global Photographic Assessment scale & patient satisfaction 2.Assessment of efficacy of cryotherapy with intralesional steroids & intralesional pentoxifylline using LAD Score & Global Photographic Assessment ScaleTimepoint: 1.Grading of improvement in hair growth & efficacy at 1st 2nd 3rd 4th 5th sittings using LAD Score. 2.Assessment of efficacy using Global Photographic Assessment scale at 1st 2nd 3rd 4th 5th sittings	—

Measure

Time frame

1.Assessment of hair growth with Global Photographic Assessment scale & patient satisfaction 2.Assessment of efficacy of cryotherapy with intralesional steroids & intralesional pentoxifylline using LAD Score & Global Photographic Assessment ScaleTimepoint: 1.Grading of improvement in hair growth & efficacy at 1st 2nd 3rd 4th 5th sittings using LAD Score. 2.Assessment of efficacy using Global Photographic Assessment scale at 1st 2nd 3rd 4th 5th sittings

—

Countries

India

Contacts

Public ContactAnjana Gopalakrishnan

Sri Devaraj Urs Academy of Higher Education and Research, Kolar.

rajashekardermat@sduaher.ac.in9448316136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026