Health Condition 1: F321- Major depressive disorder, singleepisode, moderate
Conditions
Interventions
Control Intervention1: Nil: Nil
Sponsors
Maulana Azad Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Age more than eighteen years Patient having major depressive episode without psychotic symptoms for at least two weeks according to ICD eleven criteria First onset MDD Patients attended and evaluated by senior residents or consultants Indication of anti depressant therapy Patients agreeing to be part of the study Brief Adherence Rating Scale more than eighty percent on follow up after eight weeks of treatment Controls Age and gender matched healthy volunteers who come to OPD of GIPMER LNH GNEC New Delhi General Health Questionnaire twelve items (GHQ less than three
Exclusion criteria
Exclusion criteria: Any other psychiatric diagnosis except MDD Substance use except nicotine containing agents Disorders due to substance use include disorders that result from a single occasion or repeated use of substances that have psychoactive properties including certain medications Acute and chronic major physical illness Independent variables MDD and its severity Anti depressant therapy Demography and socioeconomic status Patient with MDD will be treated as per SOP of Department of Psychiatry GIPMER
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD 4 T Cell count Th1 th2 th17 cell count Timepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment response treatment resistant depressionTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Madhumitha Surulirajan
Maulana Azad Medical College
Outcome results
None listed