Comparing the efficacy of TAP and ACP as intracanal medicament against E.fecalis in primary molars

Antimicrobial efficacy of Triple Antibiotic Paste and Amoxicillin Clavulanate Paste as an intracanal medicament against Enterococcus faecalis in primary molars: A Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071490

Enrollment

Registered

2024-07-29

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Triple Antibiotic Paste: The Triple Antibiotic Paste (TAP) is a mixture of three antimicrobials, namely, Metronidazole, Ciprofloxacin and Minocycline. It has been suggested as an intrac

Eligibility

Inclusion criteria

Inclusion criteria: 24 children in the age group of 4-8 years with open carious lesions in their maxillary or mandibular primary molars with pulp exposure and radiograph revealing interradicular/periapical radiolucencies with no history of taking any antibiotics for last 3 months

Exclusion criteria

Exclusion criteria: Teeth with Vital pulp, grade III tooth mobility and medically compromised children.

Design outcomes

Primary

Measure	Time frame
antimicrobial efficacy of TAP and ACP as an intracanal medicament against E.faecalis in primary molars.Timepoint: 2 years	—

Secondary

Measure	Time frame
ntibacterial efficacy of the intracanal medicaments- Triple Antibiotic Paste, Amoxicillin Clavulanate Paste & Calcium hydroxide.Timepoint: Baseline, 1week	—

Countries

India

Contacts

Public ContactDrVRathina

Meenakshi ammal dental college and hospital

drparisa.pedo@madch.edu.in8072847427

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026