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A study comparing local injection of drugs bupivacaine versus oxytocin for postoperative pain relief in gynaecological laparoscopic surgeries

Local infiltration of bupivacaine versus oxytocin for postoperative analgesia in gynaecological laparoscopic surgeries - A randomized controlled trial - Nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071449
Enrollment
100
Registered
2024-07-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: local infiltration of oxytocin: local infiltration of oxytocin at the port site will be done at the end of gynecological laparoscopic surgery- A single injection Intervention2: local in

Sponsors

SDMCMSH, MANJUSHREE NAGAR, SATTUR, DHARWAD
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women undergoing elective gynaecological laparoscopic surgeries ASA physical status I and II patients. BMI 30 and above

Exclusion criteria

Exclusion criteria: Pregnant patients Surgery duration more than 4 hours. ASA physical status III and IV patients. Patients with pre-existing chronic pain conditions Patients with pre-existing cardiovascular, respiratory, neurological, psychological, hepatic or renal disease.

Design outcomes

Primary

MeasureTime frame
Post-operative analgesia achieved by port site local infiltration of 5 IU of oxytocin ( 8 ml ) and 0.25% bupivacaine (8ml ) Timepoint: VAS score on arrival to PACU, 6 hours and 12 hours after surgery

Secondary

MeasureTime frame
To assess the incidence of postoperative nausea and vomitingTimepoint: on arrival to PACU, 6 hours and 12 hours after surgery

Countries

India

Contacts

Public ContactDr Anusha V Sajjan

Shri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital

sajjan.anusha119@gmail.com6362478415

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026