Health Condition 1: J17- Pneumonia in diseases classified elsewhere
Conditions
Interventions
Intervention1: IV Dexamethasone: Inj Dexamethasone at 0.1mg/kg/dose 3 times a day for 5 days
Control Intervention1: Normal saline: IV Normal saline 5ml 3 times a day for 5 days
Sponsors
Siddannagoud salotagi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children with severe community-acquired pneumonia
Exclusion criteria
Exclusion criteria: 1. Child already on steroid therapy ( Any condition requiring 20 mg of prednisone equivalent/day or more for greater than 14 days over the last 3 months) 2. Known Immunodeficiency 3. Comorbidities Comorbidities: Cystic fibrosis, malignancy 4. Presence of pre-existing medical condition that is irreversible and expected to be fatal within 3 months 5. GI bleeding requiring transfusion or requiring withholding of feed for more than 24 hours 6. Active tuberculosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality at 28 daysTimepoint: All-cause mortality at 28 days | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality at day 90 Timepoint: 90 days;Duration of ICU hospitalization, and hospital stayTimepoint: total length of stay;Duration of mechanical ventilationTimepoint: Total duration of mechanical ventilation;Duration of oxygen supportTimepoint: Total Duration of oxygen support;New onset HAI during hospitalizationTimepoint: IPD days;Rates of septic shock, and hyperferritinemia, by day 28Timepoint: 28 days | — |
Countries
India
Contacts
Public ContactSiddannagoud Salotagi
AIIMS Raipur
Outcome results
None listed