Health Condition 1: K041- Necrosis of pulp
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Dr Setu
Eligibility
Inclusion criteria
Inclusion criteria: Medically healthy patients requiring primary endodontic treatment with diagnosis of pulp necrosis and apical abscess or apical periodontitis No associated periodontal condition- mobility under physiologic limits, absence of any periodontal pocket Periapical index score of less than 3
Exclusion criteria
Exclusion criteria: Previously initiated endodontic treatment Presence of systemic diseases Patients who had received NSAIDs or antibiotic treatment within the last three months before the study. Teeth with insufficient crown structure preventing rubber dam isolation Teeth presenting with root resorption (internal/external) or root fracture or perforation. Periodontally compromised teeth
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Correlation Coefficient between Delta R values of QLF and CFU counts obtained from culture-based analysis in root canal exudates before and after biomechanical preparation in patients diagnosed with pulp necrosis and apical periodontitis/apical abscess. 2.Correlation coefficient between Delta R values of QLF and microbial counts obtained using real time PCR in root canal exudates before and after biomechanical preparation in patients diagnosed with pulp necrosis and apical periodontitis/apical abscess.Timepoint: After access opening and after biomechanical preparation on the same day | — |
Secondary
| Measure | Time frame |
|---|---|
| Quantitative assessment of changes in microbial count in root canal exudate assessed using CFU count and real time PCR before and after biomechanical preparation.Timepoint: After access opening and after biomechanical preparation on the same day | — |
Countries
India
Contacts
Public ContactDr Setu
Maulana Azad Institute of Dental Sciences
Outcome results
None listed