Health Condition 1: F31- Bipolar disorder Health Condition 2: F32- Major depressive disorder, singleepisode
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male and Female patients aged 18-65 years who will be fulfilling DSM-5 criteria for bipolar affective disorder and unipolar depression. 2. Patients who will be medically stable. 3. Patients who will be giving written informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous or concurrent systemic disease (e.g., Hypertension, Diabetes mellitus) that may affect the eyes. 2. History of ophthalmological or neurological disease known to affect the visual pathway (e.g., Glaucoma, age-related macular degeneration, diabetic retinopathy, degenerative myopia). 3. Media opacification such as cataract, corneal leukoma, or vitreous haemorrhage that impede ocular and OCT examination. 4. History of traumatic head injury with loss of consciousness and seizures. 5. Drug or alcohol or Substance dependence. 6. Extremes of ages and other causes of bipolar disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To estimate the prevalence of RNFL thickness in patients of bipolar depression, unipolar depression compared to normal population. To determine correlation of at-risk factors of socio-demographic variables, duration of illness and severity with RNFL thickness of bipolar depression, unipolar depression compared to normal population To determine association and causality of factors for RNFL thickness in bipolar depression, unipolar depression compared to normal population Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| To estimate prevalence of RNFL thickness in patients of bipolar depression, unipolar depression compared to normal population. To determine correlation of at-risk factors of socio-demographic variables, duration of illness & severity with RNFL thickness of bipolar depression, unipolar depression compared to normal population To determine association & causality of factors for RNFL thickness in bipolar depression, unipolar depression compared to normal population Timepoint: Baseline | — |
Countries
India
Contacts
Department of Psychiatry Government Medical college and Rajindra hospital Patiala