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Retinal nerve fibre layer ki thickness ka use as a biomarker for early detection of bipolar depression from uniplar depression

Retinal nerve fibre layer thickness as a biomarker for early detection of bipolar depression from unipolar depression - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/07/071402
Enrollment
225
Registered
2024-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F31- Bipolar disorder Health Condition 2: F32- Major depressive disorder, singleepisode

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Manpreet Kaur Virk
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Male and Female patients aged 18-65 years who will be fulfilling DSM-5 criteria for bipolar affective disorder and unipolar depression. 2. Patients who will be medically stable. 3. Patients who will be giving written informed consent.

Exclusion criteria

Exclusion criteria: 1. Previous or concurrent systemic disease (e.g., Hypertension, Diabetes mellitus) that may affect the eyes. 2. History of ophthalmological or neurological disease known to affect the visual pathway (e.g., Glaucoma, age-related macular degeneration, diabetic retinopathy, degenerative myopia). 3. Media opacification such as cataract, corneal leukoma, or vitreous haemorrhage that impede ocular and OCT examination. 4. History of traumatic head injury with loss of consciousness and seizures. 5. Drug or alcohol or Substance dependence. 6. Extremes of ages and other causes of bipolar disorders.

Design outcomes

Primary

MeasureTime frame
To estimate the prevalence of RNFL thickness in patients of bipolar depression, unipolar depression compared to normal population. To determine correlation of at-risk factors of socio-demographic variables, duration of illness and severity with RNFL thickness of bipolar depression, unipolar depression compared to normal population To determine association and causality of factors for RNFL thickness in bipolar depression, unipolar depression compared to normal population Timepoint: Baseline

Secondary

MeasureTime frame
To estimate prevalence of RNFL thickness in patients of bipolar depression, unipolar depression compared to normal population. To determine correlation of at-risk factors of socio-demographic variables, duration of illness & severity with RNFL thickness of bipolar depression, unipolar depression compared to normal population To determine association & causality of factors for RNFL thickness in bipolar depression, unipolar depression compared to normal population Timepoint: Baseline

Countries

India

Contacts

Public ContactDr Rajnish Raj

Department of Psychiatry Government Medical college and Rajindra hospital Patiala

profheadpsy@yahoo.com9814913599

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026