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Comparing injectable platelet rich fibrin with allograft and amniotic membrane with probiotics with allograft and amniotic membrane in intrabony defects using papilla preservation approach

Role of injectable platelet rich fibrin and allograft with amniotic membrane vs probiotic and allograft with amniotic membrane in intrabony defects using nonincised papillae surgical approach- A randomized clinical trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071401
Enrollment
22
Registered
2024-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Group 1- 11 iPRF +allograft +amniotic membrane: Injectable Platelet rich fibrin with allograft and amniotic membrane using Non Incised Papilla Surgical Approach (NIPSA) in Intrabony def

Sponsors

Panineeya Mahavidyalaya Institute of Dental Sciences and research centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Patients aged = 20 years with Stage III periodontitis • Patient having at least one tooth with intra bony defect =3mm {two wall or combined two to three walled intraosseous defect} (assessed by trans-gingival probing, radiographic examination) • CAL= 5mm • PD =6 mm.

Exclusion criteria

Exclusion criteria: • Any systemic disease that contra-indicates periodontal surgery or may affect healing. • Smokers • Pregnant and lactating mothers • History of intake of antibiotics or other medications affecting the periodontium in the previous 6 months. • Surgical periodontal therapy carried out in the past 6 months.

Design outcomes

Primary

MeasureTime frame
•Probing pocket depth(PPD) •Clinical Attachment level(CAL) •Bone fill assessed by CBCT Timepoint: Baseline and 6 months

Secondary

MeasureTime frame
• Recession depth (RD) • Location of the tip of the papilla (LTP) • Wound closure (WC)Timepoint: Baseline and 6 months

Countries

India

Contacts

Public ContactKVidya Pranathi

Panineeya Mahavidyalaya Institute of dental sciences and research centre

rekhasarat2304@gmail.com9885160094

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026