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A study to compare two different radiotherapy treatment plan with PSMA PET and with CEMRI in high-grade gliomas

Comparative analysis of radiotherapy target volumes with PSMA PET CT and CEMRI in high-grade gliomas - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/07/071381
Enrollment
27
Registered
2024-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C718- Malignant neoplasm of overlappingsites of brain

Interventions

Control Intervention1: CEMRI Brain: After 4 weeks of post-surgery CEMRI of whole brain will be done. MRI will be done once for radiotherapy treatment planning. Control Intervention2: NIL: NIL Control

Sponsors

Dr Souvik Mondal
Lead Sponsor
Dr Deepak Kumar Das
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Karnowski Performance Status 80-100 2.Post-surgery patients of WHO grade 3 or 4 gliomas

Exclusion criteria

Exclusion criteria: 1.Karnowski Performance Status 70-0 2.Inoperable patients of high-grade gliomas 3.Patient already received some cancer treatment 4.Patients with chronic kidney disease 5.Pregnant patient 6.Patients with heart disease 7.Patients with distant metastasis 8.Significant comorbidities 9.Recurrent disease

Design outcomes

Primary

MeasureTime frame
To compare the radiotherapy target volumes between postoperative CEMRI and PSMA PET of high-grade gliomasTimepoint: Minimum 1 month post surgery—

Secondary

MeasureTime frame
To compare the dosimetry of the target and organ at risk between the radiotherapy treatment plan based on CEMRI and PSMA PET CT.Timepoint: Minimum 1 month post surgery—

Countries

India

Contacts

Public ContactDr Souvik Mondal

AIIMS Bhubaneswar

radonc_deepak@aiimsbhubaneswar.edu.in7978760783

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026