Impact of coconut oil massage on weight gain in premature infants

Effect of coconut oil massage on the weight gain velocity in preterm neonates: An open label randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071344

Enrollment

140

Registered

2024-07-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P073- Preterm [premature] newborn [other]

Interventions

Intervention1: Coconut oil massage: The preterm neonates will receive moderate pressure massage therapy using edible coconut oil (4 g/kg body weight). Oil massage will be done by mothers/trained staff

Eligibility

Inclusion criteria

Inclusion criteria: Medically stable preterm neonates between 28+0 weeks and 32+6 weeks gestation will be enrolled at 72 hours of birth.

Exclusion criteria

Exclusion criteria: Babies who had a major congenital anomaly, those whose parents will refuse to give consent, had hydrops, generalized skin disorders or bleeding tendencies, presence of fracture and those who had intraventricular hemorrhage (grade 2 or more) at the time of enrolment.

Design outcomes

Primary

Measure	Time frame
Weight gain velocity (g/kg/day)Timepoint: At the time of enrolment (baseline) and then weight gain in g/kg/day at 4 weeks	—

Secondary

Measure	Time frame
Head circumference gain velocity (cm/week)Timepoint: At the time of enrollment and weekly till 4 weeks;Insulin like growth factor (IGF-1) levelsTimepoint: After 4 weeks of intervention;Intraventricular hemorrhage (grade 2 or more)Timepoint: At the time of enrollment and after 4 weeks of intervention;Length gain velocity (cm/week)Timepoint: At the time of enrollment and weekly till 4 weeks;Neonatal mortalityTimepoint: At 4 weeks of age;Parathyroid hormone (PTH) levelsTimepoint: After 4 weeks of intervention;Proven/probable sepsisTimepoint: At the time of enrollment and during hospital stay;Salivary cortisol levelsTimepoint: After 4 weeks of intervention;Serum calcium, phosphorus, alkaline phosphatase and triglycerides levelsTimepoint: At the time of enrollment and after 4 weeks of intervention;Total serum bilirubin (peak value)Timepoint: During routine clinical care till 4 weeks of intervention;Urinary creatinine & phosphorus and Tubular reabsorption of phosphate (TRP)Timepoint: After 4 weeks of intervention;Vitamin D levelsTimepoint: After 4 weeks of intervention	—

Measure

Time frame

Head circumference gain velocity (cm/week)Timepoint: At the time of enrollment and weekly till 4 weeks;Insulin like growth factor (IGF-1) levelsTimepoint: After 4 weeks of intervention;Intraventricular hemorrhage (grade 2 or more)Timepoint: At the time of enrollment and after 4 weeks of intervention;Length gain velocity (cm/week)Timepoint: At the time of enrollment and weekly till 4 weeks;Neonatal mortalityTimepoint: At 4 weeks of age;Parathyroid hormone (PTH) levelsTimepoint: After 4 weeks of intervention;Proven/probable sepsisTimepoint: At the time of enrollment and during hospital stay;Salivary cortisol levelsTimepoint: After 4 weeks of intervention;Serum calcium, phosphorus, alkaline phosphatase and triglycerides levelsTimepoint: At the time of enrollment and after 4 weeks of intervention;Total serum bilirubin (peak value)Timepoint: During routine clinical care till 4 weeks of intervention;Urinary creatinine & phosphorus and Tubular reabsorption of phosphate (TRP)Timepoint: After 4 weeks of intervention;Vitamin D levelsTimepoint: After 4 weeks of intervention

—

Countries

India

Contacts

Public ContactDr Renuka Baloda

Government Medical College and Hospital, Chandigarh

dr.sukshamj@gmail.com9988901596

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026