Health Condition 1: 8- Other Procedures
Conditions
Interventions
Intervention1: Advanced Platelet-Rich Fibrin (A-PRF): 15ml of venous blood will be drawn from the patients arm and centrifuged at 1500 rpm for 14 minutes to obtain A-PRF clots. Dressing procedure will
Sponsors
Dr Ranganath V S
Eligibility
Inclusion criteria
Inclusion criteria: Participants with chronic wound for more than six weeks and have failed to heal by conventional treatments. Wound size of less than 20cm2. Both male and female participants. Age 20 years or older. Have a normal platelet count in range of 1,50,000- 4,50,000 cells/mm3. Have a normal PT time: 11- 16 seconds. Ability to provide informed consent or have a legally authorized representative able to provide consent on behalf of the participant. Willingness to comply with study procedures and follow-up visits. Adequate understanding of the study requirements and ability to communicate with study personnel.
Exclusion criteria
Exclusion criteria: Presence of an active infection at the ulcer site. Patients on anticoagulants (warfarin, heparin). Pregnant and lactating women. Patients suffering from leukaemia, septicaemia, impaired platelet function or other haematological disorders. Patients with hypoproteinaemia. Patients taking long term steroid containing drugs or using steroid ointments on wounds.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in mean size reduction of wound area from the baseline wound size.Timepoint: Evaluation of wound size at week 2 and week 4 from baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Participants Quality of Life using Wound QoL-17 Questionnaire.Timepoint: Evaluation of Participants Quality of Life at week 2 and week 4 from baseline. | — |
Countries
India
Contacts
Public ContactJasmine S
Gautham College of Pharmacy
Outcome results
None listed