Health Condition 1: K051- Chronic gingivitis Health Condition 2: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Dr Santo Grace
Eligibility
Inclusion criteria
Inclusion criteria: The study participants are categorized into 3 groups based on the diagnosis. 1. Clinically healthy gingiva ( no bleeding, no calculus, pocket depth less than 3 mm, no clinical attachment loss) 2. Biofilm induced Gingivitis ( bleeding and calculus present. Pocket depth less than 3mm, no clinical attachment loss) 3. Stage III/IV Grade A Periodontitis ( cleeding and calculus present, pocket depth more than 5 mm, clinical attachment loss more than 2 mm)
Exclusion criteria
Exclusion criteria: 1.Presence of metabolic diseases 2.Presence of heart diseases or blood pressure alteration, renal, hepatic, gastrointestinal disease that requires a medication; presence of sexually transmitted disease, HIV, HCV infection. 3.Presence of a genetic disorder that could interfere with the evaluation of the study objectives. 4.Chronic obstructive pulmonary disease and asthma. 5.Presence of any neoplastic lesion or cancer or paraneoplastic syndrome. 6.Current radiotherapy or chemotherapy. 7.More than 8 missing teeth, with missing teeth, accounted for by third molar extractions, teeth extracted for orthodontic purposes, teeth extracted because of trauma, or congenitally missing teeth. 8.Presence of orthodontic appliances. 9.Presence of tumors or significant pathology of the soft or hard tissues of the oral cavity (such as erythroplakia, leukoplakia, candidiasis) 10.Clinically meaningful halitosis as determined by organoleptic assessment by an experienced clinician. 11.Untreated carious lesions or oral abscesses 12.Current or past (within 3 months before enrolment) assumption of medications that may influence periodontal conditions and/or interfere with healing following periodontal treatment (i.e., corticosteroids, calcium channel blockers, systemic antibiotics). 13.Patients who underwent previous oral prophylaxis in the last 6 months. 14.Patients who have taken antibiotics for the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metagenomic resistome profiles of periodontally healthy, gingivitis and periodontitis patientsTimepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of the suitable anti-microbial agent for patients with periodontitisTimepoint: baseline | — |
Countries
India
Contacts
Public ContactSanto Grace
SRM Dental College, Ramapuram
Outcome results
None listed