To find out the effectiveness of sodium alendronate gel in flap surgery with laser therapy

Comparative Evaluation of Clinical Efficacy of Topical 1% Sodium Alendronate gel as an adjunct to open flap debridement with laser biostimulation in the treatment of chronic periodontitis : A Split Mouth Randomized Controlled Clinical Trial. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071279

Enrollment

Registered

2024-07-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: With 1% Sodium Alendronate gel with laser biostimulation: This group will be treated with 1% Sodium Alendronate gel(bisphosphonates drug) with low level laser therapy in flap surgery i

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients aged from 25 to 50 year both gender 2.Patients afflicted with Chronic Periodontitis as per (AAP classification 2017) with Probing depth- = to 4mm and = 7mm 3.Radiographic evidence of bone loss(horizontal/vertical). 4.No usage of antibiotics in the preceding 6 months of the study

Exclusion criteria

Exclusion criteria: 1.Allergic to Alendronate/Bisphosphonate group of drugs 2.Systemic Alendronate / Bisphosphonate group of drugs therapy. 3.Smokers and tobacco chewers. 4.Immunocompromised patients. 5.Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
1.To evaluate the clinical efficacy of 1% topical application of Sodium Alendronate gel in open flap debridement of surgical management in Chronic Periodontitis. 2.To evaluate the effect of 1% topical sodium alendronate gel in open flap debridement with laser bio stimulation. Timepoint: Base line, 7days, 1month, 6 month	—

Secondary

Measure	Time frame
1.To compare and evaluate the effect of laser bio stimulation in open flap debridement. 2. To assess and compare the effect of diode laser therapy on gingival clinical parameters. Timepoint: Base line, 7days, 1month, 6 month	—

Countries

India

Contacts

Public ContactDr Kanika Aggarwal

ITS Dental College Hospital and Research Centre Greater Noida

drgunjan.dntlgn@its.edu.in9958543469

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026