Health Condition 1: L700- Acne vulgaris
Conditions
Interventions
Intervention1: Microbotox injection: Diluted botulinum toxin injection given into the skin of the face.
Control Intervention1: Isotretinoin tablets: Oral isotretinoin tablets at the dose of 20mg daily
Sponsors
Aishwarya Satyanarayana
Eligibility
Inclusion criteria
Inclusion criteria: Patients above the age of 18 years, with seborrhea which meets the criteria as per skin oiliness and acne which requires isotretinoin therapy. Patients who are willing to provide informed consent will be considered for participation in the study.
Exclusion criteria
Exclusion criteria: Patients with active infection at injection site, neuromuscular disorders, known hypersensitivity to any ingredient of the injection. Pregnant and lactating women. Patients on oral steroid therapy, anticoagulant therapy, systemic retinoid intake in the previous six months. Patients with unrealistic expectations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in the subjective seborrhea severity graded on a scale of 1 to 10, 1 being mild and 10 being severe from baseline to 3 months.Timepoint: Reduction in the subjective seborrhea severity at baseline, 4weeks, 8weeks and 12weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in the Comprehensive Acne Severity Score from baseline to 3 months.Timepoint: Baseline at 0weeks, follow up visits at 4,8,12 weeks. | — |
Countries
India
Contacts
Public ContactAishwarya Satyanarayana
Bangalore medical college and research institute, Bangalore
Outcome results
None listed