A Comparision of effects of hemodynamic changes during intraoperative period in two drugs in elective surgical cases

Comparison of haemodynamic effects of cisatracurium and rocuronium intraoperatively in elective surgical cases A Randomized controlled trial - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071172

Enrollment

Registered

2024-07-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: -

Interventions

Intervention1: Cisatracurium: AS soon as the patient enters the operation theatre, after attaching the monitors the TOF of 0 was attained and the induction was done with cisatracurium of 0.15mg/kg dos

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grades I and II. 2.Modified Mallampati class I to class II.

Exclusion criteria

Exclusion criteria: 1.Surgical procedures performed in urgent or critical situations. 2.Patients with full stomach. 3.Pregnancy. 4.Anticipated difficult airway patient. 5.Disease affecting neuromuscular transmission(myopathies). ? Family H/O neuromuscular disorder (NMD).

Design outcomes

Primary

Measure	Time frame
-To assess the effect of cisatracurium and rocuronium in terms of: 1.hemodynamic parameters:heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP),mean arterial pressure(MAP) . 2.Oxygen saturation(SpO2). Timepoint: during intraoperative period the Heart Rate, Blood Pressure, SpO2 Monitored - Every 3 Minutes for 30 Minutes Then Every 5 Minutes for 1 hours than every 15 minutes for next hours Until Surgery Completed.	—

Measure

Time frame

-To assess the effect of cisatracurium and rocuronium in terms of: 1.hemodynamic parameters:heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP),mean arterial pressure(MAP) . 2.Oxygen saturation(SpO2). Timepoint: during intraoperative period the Heart Rate, Blood Pressure, SpO2 Monitored - Every 3 Minutes for 30 Minutes Then Every 5 Minutes for 1 hours than every 15 minutes for next hours Until Surgery Completed.

—

Secondary

Measure	Time frame
To determine time taken from induction to intubation while using cisatracurium & rocuronium when train of four will be zeroTimepoint: Time taken will be approx 5 minutes by the drug from the time of induction to make train of four value zero.	—

Countries

India

Contacts

Public ContactDr Iqbal Qasim

Rohilkhand Medical College and Hospital

sarfaraz_ahm2000@yahoo.com9027347787

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026