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Efficacy of Excimer lamp in Plaque psoriasis

A prospective clinical split body study to determine treatment Efficacy of Excimer lamp 308nm compared to topical steroid clobetasol propionate 0.05 percentage in patients diagnosed with plaque psoriasis of less than 10 percentage BSA involvement - nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071144
Enrollment
31
Registered
2024-07-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L400- Psoriasis vulgaris

Interventions

Intervention1: Excimer lamp 308nm: one plaque will be treated with twice weekly sessions of excimer lamp & rest plaques of psoriasis will be treated once a day with topical steroid clobetasol propiona

Sponsors

Shreedha Anandrao Khatavkar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 years less than 60 years Patient with stable, mild to moderate plaque type psoriasis vulgaris. Patient with less than 10% body surface area of chronic plaque psoriasis. Size of the plaques between 2 cm to 3.5 cm at largest diameter (arbitrarily decided based on the size of the stencil available with the lamp).

Exclusion criteria

Exclusion criteria: Patient with evidence of infection in treating area. Patients with recurrent herpes infection. Patient who had received or had completed systemic treatment within past 8 weeks. Patient who had received any other form of phototherapy within past 4 weeks or used topical treatments within the past 2 weeks. Patient who had history of nonresponse to UVB phototherapy, koebnerization. Patients with palmoplantar psoriasis. Pregnant and lactating women. Not capable of following at twice weekly interval. More extensive body surface involvement. History of photosensitive dermatoses.

Design outcomes

Primary

MeasureTime frame
Study outcome measures will be 1. Presence or absence of thinning of plaques 2.Flattening, tanning or reduction of scales 3. Positive or negative Auspitz sign 4. Clinical evaluation based on modified local PASI score will be performed at baseline, 4 weeks, 8weeks, 12weeks compared on both sides i.e. side which is treated with excimer lamp 308nm with topical clobetasol propionate 0.05% Timepoint: Outcome will be assessed at baseline, 4weeks, 8weeks, 12weeks

Secondary

MeasureTime frame
NATimepoint: NA

Countries

India

Contacts

Public ContactDr Chitra Nayak

Topiwala national medical college and BYL Nair charitable hospital

chitranayak054@gmail.com9029495590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026