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Estimation of ingredients of saliva in children with mental problems before and after dental treatment

Estimation of Levels of Salivary Cytokines Interleukin-6 and Tumor Necrosis Factor-a in Children with Mild Intellectual Disability After Total Oral Rehabilitation- An In Vivo Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071143
Enrollment
23
Registered
2024-07-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Sponsors

Dr Aishani Baksi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children with mild intellectual disability between the age group of 3-6 years as specified by the DSM-5 classification given by the American Psychiatric association and having Intelligence Quotient in the range of 55-69. Children with mild intellectual disability having early childhood caries. Children whose parents are well motivated and have knowledge about intellectual disability and willing to give informed consent.

Exclusion criteria

Exclusion criteria: Children with moderate, severe, profound and unspecified intellectual disability as specified by the DSM-5 classification given by the American Psychiatric association. Children with Intelligence Quotient below 55, under anti-anxiety medication or with a history of seizures or with hearing and visual impairment Medically compromised children and uncooperative children Children whose parents are not willing to give their consent

Design outcomes

Primary

MeasureTime frame
Effect of total oral rehabilitation on salivary cytokinesTimepoint: Pre treatment, 1 month after treatment, 3 months after treatment

Secondary

MeasureTime frame
Oro-dental fluctuations following total oral rehabilitation and the possible link with alteration of salivary cytokine valuesTimepoint: Pre treatment, 1 month after treatment, 3 months after treatment

Countries

India

Contacts

Public ContactDr Aishani Baksi

AB Shetty Memorial Institute of Dental Sciences

aishanibaksi23@gmail.com9800930633

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026