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To study the effects of dexmedetomidine during extubation when given intranasally

Effect of intranasal dexmedetomidine in attenuating cough response during extubation - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071105
Enrollment
120
Registered
2024-07-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Dexmedetomidine intranasaly: Forty minutes before extubation intranasal dexmedetomidine (1mcg/kg) will be given intranasally. Cough grade will be evaluated at the time of extubation Con

Sponsors

MS Ramaiah Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18 and 60 years old of either gender. American society of Anaesthesiologists physical status (ASA) 1 and 2

Exclusion criteria

Exclusion criteria: Refusal to consent for surgery Pregnant and lactating mother Severe cardiovascular, renal or hepatic disorders Patients with nasal polyps or nasal ulcers Patients with allergy to the drug Patients with anticipated difficult airway Patients undergoing surgeries in prone position

Design outcomes

Primary

MeasureTime frame
incidence and severity of cough grade during extubationTimepoint: Immediately after extubation

Secondary

MeasureTime frame
Comparison of hemodynamic parameters, extubation time and sedation score with control groupTimepoint: Hemodynamic parameters will be recorded at 4 points, before intubation, 5minutes after giving intranasal dexmedetomidine, immediately before extubation and 5 min after extubation Sedation will be measured with Ramsay Sedation Scale

Countries

India

Contacts

Public ContactDr Leena H Parate

MS Ramaiah Medical College

dr_leenag@yahoo.co.in9480525925

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026