Screening of Oral Cancer using LED based device

Design, Assembly, Testing, and Multi-Center Evaluation of a Miniature and Portable LIF System for Screening of Oral Malignancy. - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/071091

Enrollment

300

Registered

2024-07-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C049- Malignant neoplasm of floor of mouth, unspecified

Interventions

Intervention1: Collection of fluorescence spectra from oral cavity.: Using LED as a source fluorescence will be collected from the suspicious lesions of oral cavity. The collection of spectra from eac

Eligibility

Inclusion criteria

Inclusion criteria: Cases 1. Patients diagnosed clinically with oral cancer or potentially malignant oral lesions (Leukoplakia/erythroplakia) 2. Presence of oral lesions suspected to be malignant or potentially malignant and requiring tissue biopsy. 3.No oral cancer surgery, chemotherapy or radiotherapy, or recurrences. Control: 1. patients undergoing excision of clinically benign oral soft tissue (as in pericoronal flap excision/ gingival overgrowth excision). 2. Absence of oral lesions suspected to be malignant or potentially malignant but requiring surgical excision of oral tissue as mentioned above. 3.No medical contraindication for oral soft tissue excision.

Exclusion criteria

Exclusion criteria: Cases 1. Patients diagnosed clinically with oral cancer or potentially malignant oral lesions (Leukoplakia/erythroplakia) 2. Presence of oral lesions suspected to be malignant or potentially malignant and requiring tissue biopsy. 3.No oral cancer surgery, chemotherapy or radiotherapy, or recurrences. Control: 1. patients undergoing excision of clinically benign oral soft tissue (as in pericoronal flap excision/ gingival overgrowth excision). 2. Absence of oral lesions suspected to be malignant or potentially malignant but requiring surgical excision of oral tissue as mentioned above. 3.No medical contraindication for oral soft tissue excision.

Design outcomes

Primary

Measure	Time frame
A handheld LED based optical device for the Screening of Oral Malignancy.Timepoint: 3 years	—

Secondary

Measure	Time frame
This device can be utilized to screen the other epithelial cancers such as cervical cancer.Timepoint: 1 Year	—

Countries

India

Contacts

Public ContactDr Jijo Lukose

Department of Atomic and Molecular Physics,, Manipal, MAHE

jijolks@gmail.com8310284970

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026