Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: lignocaine and dexmedetomidine: Patients will be nebulised with 4 ml 4% lignocaine + dexmedetomidine 1 microgram/kg diluted to total volume of 5 ml and haemodynamic parameters will be
Sponsors
Dr Monika
Eligibility
Inclusion criteria
Inclusion criteria: Sixty patients of age 18 to 65 yrs belonging to ASA I-II and modified Mallampati classification grade I-II scheduled for elective surgery under general anaesthesia with endotracheal intubation
Exclusion criteria
Exclusion criteria: Patients having anticipated difficult intubation will be excluded . Males and females less than 18 years and more than 45 years will be excluded . Tracheal intubation time more than 40 sec will be excluded.History of allergy to study drugs and BMI more than 30 will be excluded A history of chronic alcoholic smoker and pregnant patient will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the changes in Heart rate (HR).Timepoint: At 3 min post intubation with nebulised lignocaine,dexmedetomidine and combination of lignocaine and dexmedetomidine in patients undergoing surgery under general anaesthesia . | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To observe the changes in Heart rate ,Systolic BP ,Diastolic BP ,Mean Arterial Pressure post intubation after nebulisation with lignocaine,dexmedetomidine and combination of nebulised lignocaine and dexmedetomidine in patients undergoing surgery under general anaesthesia. 2.Incidence of coughing and bucking at intubation 3.Incidence of hypotension or bradycardia till 10 mins post intubation 4.To note the presence of coughs d it’s grading at extubationTimepoint: To record HR, SBP, DBP and MAP At prenebulisation and post nebulisation . And at 1,3,5,10 min post intubation | — |
Countries
India
Contacts
Public ContactDr Rama Wason
ESIC Medical College and Hospital,Faridabad
Outcome results
None listed