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Swallowing therapy for patients with head neck cancer treated with chemoradiation therapy: A Randomized Control Trial

Prophylactic Swallowing Exercises among Head and Neck Cancer Patients Treated with Chemo Radiation Therapy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/071024
Enrollment
44
Registered
2024-07-22
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C103- Malignant neoplasm of posterior wall of oropharynx

Interventions

Intervention1: Prophylactic Swallowing Exercises: Developed a protocol with a literature review on various exercises to improve swallowing, such as Masako, CTAR, shaker, and mobility of the jaw and to

Sponsors

Sri Ramachandra Hospital and Medical Center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: It is proposed to enrol a cohort of HNC adults>= 18 years of age, both sexes, newly diagnosed carcinoma of the oropharynx, hypopharynx, or supraglottic larynx with squamous cell carcinoma histology in stages T2-T4, N+, and M0. Patients who will have to be scheduled for chemotherapy with IMRT with a dose of 66 Gy in 33 fractions of the gross tumor volume and involved nodal disease over 6.5 weeks with chemotherapy and are willing to participate will be included.

Exclusion criteria

Exclusion criteria: Patients other than the oropharynx, hypopharynx, and supraglottic larynx or with distant metastasis will be excluded from the study. Also, patients with a history of recurrence, head and neck surgery, or surgery scheduled due to HNC or co-morbid neurological deficits or diseases affecting swallowing function will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
Swallowing physiology measured using Modified Barium Swallow studyTimepoint: Baseline and 3 months post-Chemoradiation therapy

Secondary

MeasureTime frame
Patient and clinician measuresTimepoint: Basline, Weekly during CRT, Post CRT, and 3 months post CRT

Countries

India

Contacts

Public ContactJasmine Lydia Selvaraj

Sri Ramachandra Institute of Higher Education and Research (DU)

lakshmiv@sriramachandra.edu.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026