Health Condition 1: C103- Malignant neoplasm of posterior wall of oropharynx
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: It is proposed to enrol a cohort of HNC adults>= 18 years of age, both sexes, newly diagnosed carcinoma of the oropharynx, hypopharynx, or supraglottic larynx with squamous cell carcinoma histology in stages T2-T4, N+, and M0. Patients who will have to be scheduled for chemotherapy with IMRT with a dose of 66 Gy in 33 fractions of the gross tumor volume and involved nodal disease over 6.5 weeks with chemotherapy and are willing to participate will be included.
Exclusion criteria
Exclusion criteria: Patients other than the oropharynx, hypopharynx, and supraglottic larynx or with distant metastasis will be excluded from the study. Also, patients with a history of recurrence, head and neck surgery, or surgery scheduled due to HNC or co-morbid neurological deficits or diseases affecting swallowing function will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Swallowing physiology measured using Modified Barium Swallow studyTimepoint: Baseline and 3 months post-Chemoradiation therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient and clinician measuresTimepoint: Basline, Weekly during CRT, Post CRT, and 3 months post CRT | — |
Countries
India
Contacts
Sri Ramachandra Institute of Higher Education and Research (DU)