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Effect of tACS brain stimulation on inhibitory control of Alcohol Use Disorder patients

Neuromodulatory correlates of Alpha tACS on Inhibitory Control in Alcohol Use Disorders: A sham-controlled fMRI-tACS study

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070995
Enrollment
60
Registered
2024-07-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H- Substance Abuse Treatment

Interventions

Intervention1: Alpha tACS: Alpha tACS over ACC region in patients with alcohol use disorders to be given for 5 days (one session per day). Control Intervention1: Sham tACS: Sham tACS over ACC region i

Sponsors

Central Institute of Psychiatry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Male patients diagnosed with Alcohol Dependence Syndrome as per International Classification of Disease - 10th revision - Diagnostic Criteria for Research. Male with Alcohol Dependence aged between 18 to 50 years. Severity of Alcohol Dependence Questionnaire (SADQ) in Male with Alcohol dependence greater than 16. The Clinical Institute Withdrawal Assessment for Alcohol (revised version) in Male with Alcohol dependence CIWA-Ar lesser than or equal to 7. Right-handed. Males with Alcohol dependence who are ready to give informed consent.

Exclusion criteria

Exclusion criteria: Male with Alcohol dependence having any other co-morbid substance dependence. Male with Alcohol dependence having any medical illness. Male with Alcohol dependence having any other psychiatric illness, dementia, psychotic disorder. Male with Alcohol dependence who are on any psychotropic medication in 2 weeks preceding and during the study. Male with Alcohol dependence who have received ECT in past 6 months. Colour blind. Male with Alcohol dependence having any metallic implants/parts in the body.

Design outcomes

Primary

MeasureTime frame
Effectiveness of Alpha tACS on inhibitory control in patients with alcohol use disordersTimepoint: Baseline, 5 days

Secondary

MeasureTime frame
fMRI activation of ACC using Alcoholic Go/No Go task in patients of Alcohol Use DisordersTimepoint: Baseline, 5 days

Countries

India

Contacts

Public ContactAlok Pratap

Central Institute of Psychiatry

dralokpratap@gmail.com7781803812

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026