Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified
Conditions
Interventions
Intervention1: Injectable Platelet Rich Fibrin: Submucosal injection of i-PRF on the day of extraction and 15 days post extraction
(2mL and 1mL of i-PRF injected in the submucosa on the buccal and pa
Sponsors
ITS Dental College, Hospital and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: Patients requiring extraction of upper first premolars for orthodontic treatment. Patients without any systemic diseases or medications that affect tooth movement. Patients with healthy periodontium and good oral hygiene. Patients giving informed consent and volunteering to participate in the study.
Exclusion criteria
Exclusion criteria: Patients with history of long-term medication such as non-steroidal anti-inflammatory drugs and hormone supplements, known to interfere with bone metabolism. Patients with unilateral chewing or para functional habits, skeletal cross bite, or occlusal interferences. Periodontally compromised patients with poor bone quality affecting orthodontic tooth movement. Patients with impacted canines. Patients with any craniofacial anomalies or temporomandibular disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accelerated tooth movement on the side of i-PRF injectionTimepoint: Weeks 1, 4, 8 and 12 | — |
Secondary
| Measure | Time frame |
|---|---|
| Increased levels of IL-betaTimepoint: Days 1,15 | — |
Countries
India
Contacts
Public ContactDr Rajeshwar Singh
ITS Dental college Greater Noida
Outcome results
None listed